ML 786 dihydrochloride

Catalog No. A11211

ML 786 dihydrochloride是一种有效的Raf激酶抑制剂(B-RafV600E,C-Raf和野生型B-Raf的IC50值分别为2.1、2.5和4.2 nM)。
Catalog Num A11211
M. Wt 611.48
Formula C29H29F3N4O3.2HCl
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 1237536-18-3
Synonyms ML786 dihydrochloride
SMILES CC(C)(C1=CC(=CC(=C1)C(=O)NC2CCC3=C(C2)C=C(C=C3)OC4=C5CCC(=O)NC5=NC=C4)C(F)(F)F)N.Cl.Cl
ML 786 dihydrochloride是一种有效的Raf激酶抑制剂(B-RafV600E,C-Raf和野生型B-Raf的IC50值分别为2.1、2.5和4.2 nM)。
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 16.35 mL 81.77 mL 163.54 mL
0.5 mM 3.27 mL 16.35 mL 32.71 mL
1 mM 1.64 mL 8.18 mL 16.35 mL
5 mM 0.33 mL 1.64 mL 3.27 mL

*The above data is based on the productmolecular weight 611.48. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.