Ticagrelor (AZD6140)

Catalog No. A11238

Ticagrelor (AZD6140)是第一个可逆结合的口服P2Y（12）受体拮抗剂，可阻断ADP诱导的血小板聚集。

Technical details

Catalog Num	A11238
M. Wt	522.6
Formula	C23H28F2N6O4S
Purity	>98%
Storage	at -20°C 3 years Powder
CAS No.	274693-27-5
Synonyms	AZD 6140
SMILES	CCCSC1=NC2=C(C(=N1)N[C@@H]3C[C@H]3C4=CC(=C(C=C4)F)F)N=NN2[C@@H]5C[C@@H]([C@H]([C@H]5O)O)OCCO

Biological Activity

Ticagrelor (AZD6140)是第一个可逆结合的口服P2Y（12）受体拮抗剂，可阻断ADP诱导的血小板聚集。

Solubility *

In vitro (25°C)	DMSO	99 mg/mL (189.45 mM)
	Water	Insoluble
	Ethanol	52 mg/mL (99.51 mM)
In vivo	2% DMSO+30% PEG 300+5% Tween 80+ddH2O	9 mg/mL
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	19.14 mL	95.68 mL	191.35 mL
0.5 mM	3.83 mL	19.14 mL	38.27 mL
1 mM	1.91 mL	9.57 mL	19.14 mL
5 mM	0.38 mL	1.91 mL	3.83 mL

*The above data is based on the productmolecular weight 522.6 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Adooq Bioscience

Ticagrelor (AZD6140)

Technical details

Biological Activity

Solubility *

Preparing Stock Solutions