MLN2480 (BIIB-024)

Catalog No. A11240

MLN2480 (BIIB-024)是一种口服的Raf激酶抑制剂。

Technical details

Catalog Num	A11240
M. Wt	506.29
Formula	C17H12Cl2F3N7O2S
Purity	>98%
Storage	at -20°C 3 years Powder
CAS No.	1096708-71-2
Synonyms	MLN-2480,BIIB 024, BIIB-024
SMILES	C[C@H](C1=NC=C(S1)C(=O)NC2=NC=C(C(=C2)C(F)(F)F)Cl)NC(=O)C3=C(C(=NC=N3)N)Cl

Biological Activity

MLN2480 (BIIB-024)是一种口服的Raf激酶抑制剂。

Targets

Raf

Solubility *

In vitro	DMSO	95 mg/mL (187.63 mM)
	Water	Insoluble
	Ethanol	95 mg/mL (187.63 mM)
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	19.75 mL	98.76 mL	197.52 mL
0.5 mM	3.95 mL	19.75 mL	39.5 mL
1 mM	1.98 mL	9.88 mL	19.75 mL
5 mM	0.4 mL	1.98 mL	3.95 mL

*The above data is based on the productmolecular weight 506.29. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.