PF-03084014

Catalog No. A11259

PF-03084014是一种可逆和选择性的γ-分泌酶抑制剂,IC50值为6.2 nM。
Catalog Num A11259
M. Wt 489.64
Formula C27H41F2N5O
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 865773-15-5, 1290543-63-3
Synonyms PF 03084014, PF03084014
SMILES CCC[C@@H](C(=O)NC1=CN(C=N1)C(C)(C)CNCC(C)(C)C)N[C@H]2CCC3=CC(=CC(=C3C2)F)F
PF-03084014是一种可逆和选择性的γ-分泌酶抑制剂,IC50值为6.2 nM。
In vitro DMSO Warmed: 89 mg/mL (181.76 mM)
Water Insoluble
Ethanol Warmed: 89 mg/mL (181.76 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 20.42 mL 102.12 mL 204.23 mL
0.5 mM 4.08 mL 20.42 mL 40.85 mL
1 mM 2.04 mL 10.21 mL 20.42 mL
5 mM 0.41 mL 2.04 mL 4.08 mL

*The above data is based on the productmolecular weight 489.64. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.