Anisomycin

Catalog No. A11271

Anisomycin是一种吡咯烷类抗生素,用作抑制蛋白质合成的抗真菌抗生素,也是SAPK/JNK的有效激活剂。
  • Ken Kobayashi, .et al. Lactose on the basolateral side of mammary epithelial cells inhibits milk production concomitantly with signal transducer and activator of transcription 5 inactivation, Cell Tissue Res, 2022, Sep;389(3):501-515 PMID: 35748981
  • Li Li, .et al. The mutual regulatory loop between TPTEP1 and miR-1303 in leukemogenesis of acute myeloid leukemia, Cancer Cell Int, 2021, May 13;21(1):260 PMID: 33985519
Catalog Num A11271
M. Wt 265.31
Formula C14H19NO4
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 22862-76-6
Synonyms Flagecidin, Wuningmeisu C
SMILES O[C@@H]1[C@H]([C@@H](CC(C=C2)=CC=C2OC)NC1)OC(C)=O
Anisomycin是一种吡咯烷类抗生素,用作抑制蛋白质合成的抗真菌抗生素,也是SAPK/JNK的有效激活剂。
Targets
JNK
In vitro (25°C) DMSO Warmed: 35 mg/mL (131.92 mM)
Water Insoluble
Ethanol Warmed: 14 mg/mL (52.76 mM)
In vivo 2% DMSO+corn oil 4 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 37.69 mL 188.46 mL 376.92 mL
0.5 mM 7.54 mL 37.69 mL 75.38 mL
1 mM 3.77 mL 18.85 mL 37.69 mL
5 mM 0.75 mL 3.77 mL 7.54 mL

*The above data is based on the productmolecular weight 265.31. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.