CGI1746

Catalog No. A11348

CGI1746是具有新结合模式的小分子Btk抑制剂化学型，可稳定无活性的非磷酸化酶构象。

Technical details

Catalog Num	A11348
M. Wt	579.7
Formula	C34H37N5O4
Purity	>98%
Storage	at -20°C 3 years Powder
CAS No.	910232-84-7
Synonyms	CGI 1746, CGI-1746
SMILES	CC1=C(C=CC=C1NC(=O)C2=CC=C(C=C2)C(C)(C)C)C3=CN(C(=O)C(=N3)NC4=CC=C(C=C4)C(=O)N5CCOCC5)C

Biological Activity

CGI1746是具有新结合模式的小分子Btk抑制剂化学型，可稳定无活性的非磷酸化酶构象。

Targets

BTK
1.9 nM

Solubility *

In vitro	DMSO	91 mg/mL (156.98 mM)
	Water	Insoluble
	Ethanol	Warmed: 30 mg/mL (51.75 mM)
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	17.25 mL	86.25 mL	172.5 mL
0.5 mM	3.45 mL	17.25 mL	34.5 mL
1 mM	1.73 mL	8.63 mL	17.25 mL
5 mM	0.35 mL	1.73 mL	3.45 mL

*The above data is based on the productmolecular weight 579.7 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.