E 2012

Catalog No. A11393

E 2012是γ-secretase抑制剂。
  • Yesuvadian R, .et al. Potent γ-secretase inhibitors/modulators interact with amyloid-β fibrils but do not inhibit fibrillation: a high-resolution NMR study., Biochem Biophys Res Commun., 2014, May 16;447(4):590-5 PMID: 24747079
Catalog Num A11393
M. Wt 419.49
Formula C25H26FN3O2
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 870843-42-8
Synonyms E-2012,E2012
SMILES CC1=CN(C=N1)C2=C(C=C(C=C2)/C=C/3\CCCN(C3=O)[C@@H](C)C4=CC=C(C=C4)F)OC
E 2012是γ-secretase抑制剂。
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 23.84 mL 119.19 mL 238.38 mL
0.5 mM 4.77 mL 23.84 mL 47.68 mL
1 mM 2.38 mL 11.92 mL 23.84 mL
5 mM 0.48 mL 2.38 mL 4.77 mL

*The above data is based on the productmolecular weight 419.49. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.