PF 3716556

Catalog No. A11408

PF 3716556是H+,K+-ATPase酶抑制剂(在人类重组离子渗漏试验中PIC50 = 6)。

Technical details

Catalog Num	A11408
M. Wt	394.5
Formula	C22H26N4O3
Purity	>98%
Storage	at -20°C 3 years Powder
CAS No.	928774-43-0
Synonyms	PF-3716556, PF3716556
SMILES	CC1=C2[C@@H](CCOC2=CC=C1)NC3=CC(=CN4C3=NC(=C4)C)C(=O)N(C)CCO

Biological Activity

PF 3716556是H+,K+-ATPase酶抑制剂(在人类重组离子渗漏试验中PIC50 = 6)。

Targets

H+/K+-ATPase
~6.5(pIC50)

Solubility *

In vitro	DMSO	73 mg/mL (185.05 mM)
	Water	Insoluble
	Ethanol	73 mg/mL (185.05 mM)
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	25.35 mL	126.74 mL	253.49 mL
0.5 mM	5.07 mL	25.35 mL	50.7 mL
1 mM	2.53 mL	12.67 mL	25.35 mL
5 mM	0.51 mL	2.53 mL	5.07 mL

*The above data is based on the productmolecular weight 394.5 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.