Eletriptan hydrobromide

Catalog No. A11418

Eletriptan hydrobromide是一种选择性SR-1B/SR-1D激动剂。

Product Citations

Li Li, .et al. Delineating a serotonin 1B receptor circuit for appetite suppression in mice, J Exp Med, 2022, Aug 1;219(8):e20212307 PMID: 35796804

Technical details

Catalog Num	A11418
M. Wt	463.43
Formula	C22H26N2O2S.HBr
Purity	>98%
Storage	at -20°C 3 years Powder
CAS No.	177834-92-3
Synonyms
SMILES	CN1CCC[C@@H]1CC2=CNC3=C2C=C(C=C3)CCS(=O)(=O)C4=CC=CC=C4.Br

Biological Activity

Eletriptan hydrobromide是一种选择性SR-1B/SR-1D激动剂。

Targets

5-HT1B	5-HT1D
0.92 nM(Ki)	3.14 nM(Ki)

Solubility *

In vitro	DMSO	83 mg/mL (179.09 mM)
	Water	Insoluble
	Ethanol	Insoluble
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	21.58 mL	107.89 mL	215.78 mL
0.5 mM	4.32 mL	21.58 mL	43.16 mL
1 mM	2.16 mL	10.79 mL	21.58 mL
5 mM	0.43 mL	2.16 mL	4.32 mL

*The above data is based on the productmolecular weight 463.43. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.