GW843682X
Catalog No. A11438
GW843682X是polo-like激酶1（PLK1）和polo-like激酶3（PLK3）的选择性抑制剂（IC50值分别为2.2和9.1 nM）。
- Kanada F, .et al. Histone acetyltransferase and Polo-like kinase 3 inhibitors prevent rat galactose-induced cataract, Sci Rep, 2019, Dec 27;9(1):20085 PMID: 31882756
| Catalog Num | A11438 |
|---|---|
| M. Wt | 477.46 |
| Formula | C22H18F3N3O4S |
| Purity | >98% |
| Storage | at -20°C 3 years Powder |
| CAS No. | 660868-91-7 |
| Synonyms | |
| SMILES | COC1=C(C=C2C(=C1)N=CN2C3=CC(=C(S3)C(=O)N)OCC4=CC=CC=C4C(F)(F)F)OC |
GW843682X是polo-like激酶1（PLK1）和polo-like激酶3（PLK3）的选择性抑制剂（IC50值分别为2.2和9.1 nM）。
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 20.94 mL | 104.72 mL | 209.44 mL |
| 0.5 mM | 4.19 mL | 20.94 mL | 41.89 mL |
| 1 mM | 2.09 mL | 10.47 mL | 20.94 mL |
| 5 mM | 0.42 mL | 2.09 mL | 4.19 mL |
*The above data is based on the productmolecular weight 477.46. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
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