Cathepsin Inhibitor 1

Catalog No. A11466

Cathepsin Inhibitor 1抑制剂1 是一种Cathepsin (L, L2, S, K, B)的抑制剂，pIC50分别为7.9、6.7、6.0、5.5和5.2。

Technical details

Catalog Num	A11466
M. Wt	401.89
Formula	C20H24ClN5O2
Purity	>98%
Storage	at -20°C 3 years Powder
CAS No.	225120-65-0
Synonyms
SMILES	CC(C)(C)C1=NN(C(=C1)C(=O)NC(CC2=CC(=CC=C2)Cl)C(=O)NCC#N)C

Biological Activity

Cathepsin Inhibitor 1抑制剂1 是一种Cathepsin (L, L2, S, K, B)的抑制剂，pIC50分别为7.9、6.7、6.0、5.5和5.2。

Targets

Cathepsin L	Cathepsin L2	Cathepsin S	Cathepsin K	Cathepsin S
7.9(pIC50)	6.7(pIC50)	6(pIC50)	5.5(pIC50)	5.2(pIC50)

Solubility *

In vitro	DMSO	70 mg/mL (174.17 mM)
	Water	Insoluble
	Ethanol	44 mg/mL (109.48 mM)
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	24.88 mL	124.41 mL	248.82 mL
0.5 mM	4.98 mL	24.88 mL	49.76 mL
1 mM	2.49 mL	12.44 mL	24.88 mL
5 mM	0.5 mL	2.49 mL	4.98 mL

*The above data is based on the productmolecular weight 401.89. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.