Ki 20227

Catalog No. A11472

Ki 20227是c-Fms酪氨酸激酶(M-CSFR,CSF1R)的抑制剂。
  • Wensheng Wang, .et al. Lymphatic endothelial cells produce M-CSF causing massive bone loss in mice, J Bone Miner Res, 2017, May; 32(5): 939-950 PMID: 28052488
Catalog Num A11472
M. Wt 480.54
Formula C24H24N4O5S
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 623142-96-1
Synonyms Ki-20227, Ki20227
SMILES CC(C1=NC=CS1)NC(=O)NC2=C(C=C(C=C2)OC3=C4C=C(C(=CC4=NC=C3)OC)OC)OC
Ki 20227是c-Fms酪氨酸激酶(M-CSFR,CSF1R)的抑制剂。
In vitro DMSO 94 mg/mL (195.61 mM)
Water <1 mg/mL
Ethanol 3 mg/mL (6.24 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 20.81 mL 104.05 mL 208.1 mL
0.5 mM 4.16 mL 20.81 mL 41.62 mL
1 mM 2.08 mL 10.4 mL 20.81 mL
5 mM 0.42 mL 2.08 mL 4.16 mL

*The above data is based on the productmolecular weight 480.54. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.