NVP-BAG956

Catalog No. A11511

NVP-BAG956是一种强效、可逆和ATP竞争性PI3-K/PDK1双激酶抑制剂,对VEGFR 1(IC50 = 2.56 μM)的效力大大降低,对其他15种激酶(IC50 > 10 uM)的活性很小或没有活性。
Catalog Num A11511
M. Wt 427.5
Formula C28H21N5
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 853910-02-8
Synonyms NVP-BAG 956
SMILES CC1=NC2=CN=C3C=CC(=CC3=C2N1C4=CC=C(C=C4)C(C)(C)C#N)C#CC5=CN=CC=C5
NVP-BAG956是一种强效、可逆和ATP竞争性PI3-K/PDK1双激酶抑制剂,对VEGFR 1(IC50 = 2.56 μM)的效力大大降低,对其他15种激酶(IC50 > 10 uM)的活性很小或没有活性。
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 23.39 mL 116.96 mL 233.92 mL
0.5 mM 4.68 mL 23.39 mL 46.78 mL
1 mM 2.34 mL 11.7 mL 23.39 mL
5 mM 0.47 mL 2.34 mL 4.68 mL

*The above data is based on the productmolecular weight 427.5 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.