Rilpivirine (R 278474, TMC 278)
Catalog No. A11542
Rilpivirine (R 278474,TMC 278)是第二代非核苷逆转录酶抑制剂(NNRTI),与较老的NNRTIs(例如依非韦伦)相比,具有更高的效力,更长的半衰期和更低的副作用。
Catalog Num | A11542 |
---|---|
M. Wt | 366.4 |
Formula | C22H18N6 |
Purity | >98% |
Storage | at -20°C 3 years Powder |
CAS No. | 500287-72-9 |
Synonyms | R278474, TMC278, TMC-278 |
SMILES | CC1=CC(=CC(=C1NC2=NC(=NC=C2)NC3=CC=C(C=C3)C#N)C)/C=C/C#N |
Rilpivirine (R 278474,TMC 278)是第二代非核苷逆转录酶抑制剂(NNRTI),与较老的NNRTIs(例如依非韦伦)相比,具有更高的效力,更长的半衰期和更低的副作用。
In vitro | DMSO | 66 mg/mL (180.12 mM) | |
Water | Insoluble | ||
Ethanol | Insoluble | ||
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
---|---|---|---|
0.1 mM | 27.29 mL | 136.46 mL | 272.93 mL |
0.5 mM | 5.46 mL | 27.29 mL | 54.59 mL |
1 mM | 2.73 mL | 13.65 mL | 27.29 mL |
5 mM | 0.55 mL | 2.73 mL | 5.46 mL |
*The above data is based on the productmolecular weight 366.4 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.