Duloxetine HCl
Catalog No. A11717
Duloxetine Hydrochloride是一种5-羟色胺和去甲肾上腺素再摄取抑制剂(SNRI),Ki为 4.6 nM。用于治疗压力性尿失禁和抑郁症。
Catalog Num | A11717 |
---|---|
M. Wt | 333.88 |
Formula | C18H19NOS.HCl |
Purity | >98% |
Storage | at -20°C 3 years Powder |
CAS No. | 136434-34-9 |
Synonyms | |
SMILES | CNCC[C@@H](C1=CC=CS1)OC2=CC=CC3=CC=CC=C32.Cl |
Duloxetine Hydrochloride是一种5-羟色胺和去甲肾上腺素再摄取抑制剂(SNRI),Ki为 4.6 nM。用于治疗压力性尿失禁和抑郁症。
Targets
5-HT | ||||
In vitro (25°C) | DMSO | 65 mg/mL (194.68 mM) | |
Water | Insoluble | ||
Ethanol | Insoluble | ||
In vivo | 2% DMSO+30% PEG 300+ddH2O | 19 mg/mL | |
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
---|---|---|---|
0.1 mM | 29.95 mL | 149.75 mL | 299.51 mL |
0.5 mM | 5.99 mL | 29.95 mL | 59.9 mL |
1 mM | 3 mL | 14.98 mL | 29.95 mL |
5 mM | 0.6 mL | 3 mL | 5.99 mL |
*The above data is based on the productmolecular weight 333.88. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.