Almotriptan malate (Axert)

Catalog No. A11799

Almotriptan malate (Axert)是一种选择性的5-羟色胺1B/1D(5-HT1B/1D)受体激动剂,用于治疗成人偏头痛。
  • Li Li, .et al. Delineating a serotonin 1B receptor circuit for appetite suppression in mice, J Exp Med, 2022, Aug 1;219(8):e20212307 PMID: 35796804
Catalog Num A11799
M. Wt 469.55
Formula C17H25N3O2S.C4H6O5
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 181183-52-8
Synonyms Axert
SMILES CN(C)CCC1=CNC2=C1C=C(C=C2)CS(=O)(=O)N3CCCC3.C(C(C(=O)O)O)C(=O)O
Almotriptan malate (Axert)是一种选择性的5-羟色胺1B/1D(5-HT1B/1D)受体激动剂,用于治疗成人偏头痛。
Targets
5-HT1B
5-HT1D
In vitro DMSO 86 mg/mL (183.15 mM)
Water Insoluble
Ethanol 48 mg/mL (102.22 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 21.3 mL 106.48 mL 212.97 mL
0.5 mM 4.26 mL 21.3 mL 42.59 mL
1 mM 2.13 mL 10.65 mL 21.3 mL
5 mM 0.43 mL 2.13 mL 4.26 mL

*The above data is based on the productmolecular weight 469.55. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.