Atorvastatin calcium

Catalog No. A11800

Atorvastatin calcium (Lipitor)是HMG-CoA还原酶的抑制剂，可用作降低胆固醇的药物，可阻止胆固醇的产生。

Technical details

Catalog Num	A11800
M. Wt	1155.34
Formula	2(C33H34FN2O5).Ca
Purity	>98%
Storage	at -20°C 3 years Powder
CAS No.	134523-03-8
Synonyms	Lipitor
SMILES	CC(C)C1=C(C(=C(N1CC[C@H](C[C@H](CC(=O)[O-])O)O)C2=CC=C(C=C2)F)C3=CC=CC=C3)C(=O)NC4=CC=CC=C4.CC(C)C1=C(C(=C(N1CC[C@H](C[C@H](CC(=O)[O-])O)O)C2=CC=C(C=C2)F)C3=CC=CC=C3)C(=O)NC4=CC=CC=C4.[Ca+2]

Biological Activity

Atorvastatin calcium (Lipitor)是HMG-CoA还原酶的抑制剂，可用作降低胆固醇的药物，可阻止胆固醇的产生。

Targets

HMG-CoA reductase (Cell-free assay)

Solubility *

In vitro (25°C)	DMSO	92 mg/mL (79.63 mM)
	Water	Insoluble
	Ethanol	Insoluble
In vivo	2% DMSO+35% PEG300+2% Tween 80+ddH2O	3 mg/mL
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	8.66 mL	43.28 mL	86.55 mL
0.5 mM	1.73 mL	8.66 mL	17.31 mL
1 mM	0.87 mL	4.33 mL	8.66 mL
5 mM	0.17 mL	0.87 mL	1.73 mL

*The above data is based on the productmolecular weight 1155.34. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.