Flumequine

Catalog No. A11861

Flumequine是一种合成化学抗生素，可在回旋酶/拓扑异构酶水平上影响哺乳动物染色体和DNA的解链。抑制拓扑异构酶II， IC50为15 μM。

Technical details

Catalog Num	A11861
M. Wt	261.25
Formula	C14H12FNO3
Purity	>98%
Storage	at -20°C 3 years Powder
CAS No.	42835-25-6
Synonyms
SMILES	CC1CCC2=C3N1C=C(C(=O)C3=CC(=C2)F)C(=O)O

Biological Activity

Flumequine是一种合成化学抗生素，可在回旋酶/拓扑异构酶水平上影响哺乳动物染色体和DNA的解链。抑制拓扑异构酶II， IC50为15 μM。

Targets

Topo II
15 μM

Solubility *

In vitro	DMSO	3 mg/mL (11.48 mM)
	Water	Insoluble
	Ethanol	Insoluble
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	38.28 mL	191.39 mL	382.78 mL
0.5 mM	7.66 mL	38.28 mL	76.56 mL
1 mM	3.83 mL	19.14 mL	38.28 mL
5 mM	0.77 mL	3.83 mL	7.66 mL

*The above data is based on the productmolecular weight 261.25. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.