Pravastatin sodium

Catalog No. A11912

Pravastatin sodium是3-羟基-3-甲基辅酶A(HMG-CoA)还原酶的水溶性竞争性抑制剂。有效阻断体内胆固醇合成(Ki?1 nM)并显示出心脏保护特性。
Catalog Num A11912
M. Wt 446.51
Formula C23H35NaO7
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 81131-70-6
Synonyms Eptastatin sodium
SMILES CC[C@H](C)C(=O)O[C@H]1C[C@@H](C=C2[C@H]1[C@H]([C@H](C=C2)C)CC[C@H](C[C@H](CC(=O)[O-])O)O)O.[Na+]
Pravastatin sodium是3-羟基-3-甲基辅酶A(HMG-CoA)还原酶的水溶性竞争性抑制剂。有效阻断体内胆固醇合成(Ki?1 nM)并显示出心脏保护特性。
Targets
HMG-CoA reductase
5.6 μM
In vitro DMSO 79 mg/mL (176.92 mM)
Water 79 mg/mL (176.92 mM)
Ethanol 11 mg/mL (24.63 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 22.4 mL 111.98 mL 223.96 mL
0.5 mM 4.48 mL 22.4 mL 44.79 mL
1 mM 2.24 mL 11.2 mL 22.4 mL
5 mM 0.45 mL 2.24 mL 4.48 mL

*The above data is based on the productmolecular weight 446.51. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.