Prazosin HCl

Catalog No. A11914

Prazosin HCl是一种α1和α2B肾上腺素受体拮抗剂。也是褪黑激素MT3受体的有效拮抗剂（Ki = 10.2 nM）

Product Citations

Reiko Watanabe, .et al. Development of an In Silico Prediction Model for P-glycoprotein Efflux Potential in Brain Capillary Endothelial Cells toward the Prediction of Brain Penetration, J Med Chem, 2021, Mar 11;64(5):2725-2738 PMID: 33619967

Technical details

Catalog Num	A11914
M. Wt	419.87
Formula	C19H21N5O4.HCl
Purity	>98%
Storage	at -20°C 3 years Powder
CAS No.	19237-84-4
Synonyms
SMILES	COC1=C(C=C2C(=C1)C(=NC(=N2)N3CCN(CC3)C(=O)C4=CC=CO4)N)OC.Cl

Biological Activity

Prazosin HCl是一种α1和α2B肾上腺素受体拮抗剂。也是褪黑激素MT3受体的有效拮抗剂（Ki = 10.2 nM）

Targets

alpha-adrenergic receptor

Solubility *

In vitro	DMSO	Warmed: 4 mg/mL (9.52 mM)
	Water	Insoluble
	Ethanol	Insoluble
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	23.82 mL	119.08 mL	238.17 mL
0.5 mM	4.76 mL	23.82 mL	47.63 mL
1 mM	2.38 mL	11.91 mL	23.82 mL
5 mM	0.48 mL	2.38 mL	4.76 mL

*The above data is based on the productmolecular weight 419.87. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.