Tenovin-1

Catalog No. A11943

Tenovin-1是p53转录活性的小分子激活剂，可防止MDM2介导的p53降解。

Technical details

Catalog Num	A11943
M. Wt	369.5
Formula	C20H23N3O2S
Purity	>98%
Storage	at -20°C 3 years Powder
CAS No.	380315-80-0
Synonyms
SMILES	CC(=O)NC1=CC=C(C=C1)NC(=S)NC(=O)C2=CC=C(C=C2)C(C)(C)C

Biological Activity

Tenovin-1是p53转录活性的小分子激活剂，可防止MDM2介导的p53降解。

Targets

p53	Mdm2

Solubility *

In vitro (25°C)	DMSO	65 mg/mL (175.92 mM)
	Water	Insoluble
	Ethanol	Insoluble
In vivo	15% Captisol	14 mg/mL
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	27.06 mL	135.32 mL	270.64 mL
0.5 mM	5.41 mL	27.06 mL	54.13 mL
1 mM	2.71 mL	13.53 mL	27.06 mL
5 mM	0.54 mL	2.71 mL	5.41 mL

*The above data is based on the productmolecular weight 369.5 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.