(Z)-SMI-4a
Catalog No. A11945
SIM-4a是一种Pim激酶抑制剂,可通过激活AMPK来阻断mTORC1的活性。 通常对Pim-2有效,不会显着抑制任何其他丝氨酸/苏氨酸或酪氨酸激酶。
- Liong S, .et al. Placental Pim-1 expression is increased in obesity and regulates cytokine- and toll-like receptor-mediated inflammation, Placenta, 2017, May;53:101-112 PMID: 28487013
Catalog Num | A11945 |
---|---|
M. Wt | 273.2 |
Formula | C11H6F3NO2S |
Purity | >98% |
Storage | at -20°C 3 years Powder |
CAS No. | 327033-36-3 |
Synonyms | SMI4a |
SMILES | O=C(NC/1=O)SC1=C/C2=CC=CC(C(F)(F)F)=C2 |
SIM-4a是一种Pim激酶抑制剂,可通过激活AMPK来阻断mTORC1的活性。 通常对Pim-2有效,不会显着抑制任何其他丝氨酸/苏氨酸或酪氨酸激酶。
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
---|---|---|---|
0.1 mM | 36.6 mL | 183.02 mL | 366.03 mL |
0.5 mM | 7.32 mL | 36.6 mL | 73.21 mL |
1 mM | 3.66 mL | 18.3 mL | 36.6 mL |
5 mM | 0.73 mL | 3.66 mL | 7.32 mL |
*The above data is based on the productmolecular weight 273.2 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.