PQ 401
Catalog No. A11951
PQ 401是可透过细胞的苯基喹啉基-脲化合物,可抑制IGF-1R自磷酸化,IC50为低于1 μM。
Catalog Num | A11951 |
---|---|
M. Wt | 341.79 |
Formula | C18H16ClN3O2 |
Purity | >98% |
Storage | at -20°C 3 years Powder |
CAS No. | 196868-63-0 |
Synonyms | PQ401 |
SMILES | CC1=NC2=CC=CC=C2C(=C1)NC(=O)NC3=C(C=CC(=C3)Cl)OC |
PQ 401是可透过细胞的苯基喹啉基-脲化合物,可抑制IGF-1R自磷酸化,IC50为低于1 μM。
Targets
IGF-1R | ||||
<1 μM |
In vitro (25°C) | DMSO | 30 mg/mL (87.77 mM) | |
Water | Insoluble | ||
Ethanol | Insoluble | ||
In vivo | 30% PEG400+0.5% Tween80+5% propylene glycol | 4 mg/mL | |
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
---|---|---|---|
0.1 mM | 29.26 mL | 146.29 mL | 292.58 mL |
0.5 mM | 5.85 mL | 29.26 mL | 58.52 mL |
1 mM | 2.93 mL | 14.63 mL | 29.26 mL |
5 mM | 0.59 mL | 2.93 mL | 5.85 mL |
*The above data is based on the productmolecular weight 341.79. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.