PQ 401

Catalog No. A11951

PQ 401是可透过细胞的苯基喹啉基-脲化合物,可抑制IGF-1R自磷酸化,IC50为低于1 μM。
Catalog Num A11951
M. Wt 341.79
Formula C18H16ClN3O2
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 196868-63-0
Synonyms PQ401
SMILES CC1=NC2=CC=CC=C2C(=C1)NC(=O)NC3=C(C=CC(=C3)Cl)OC
PQ 401是可透过细胞的苯基喹啉基-脲化合物,可抑制IGF-1R自磷酸化,IC50为低于1 μM。
Targets
IGF-1R
<1 μM
In vitro (25°C) DMSO 30 mg/mL (87.77 mM)
Water Insoluble
Ethanol Insoluble
In vivo 30% PEG400+0.5% Tween80+5% propylene glycol 4 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 29.26 mL 146.29 mL 292.58 mL
0.5 mM 5.85 mL 29.26 mL 58.52 mL
1 mM 2.93 mL 14.63 mL 29.26 mL
5 mM 0.59 mL 2.93 mL 5.85 mL

*The above data is based on the productmolecular weight 341.79. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.