Ki16198

Catalog No. A11966

Ki16198是有效的LPA受体拮抗剂，可抑制LPA1和LPA3诱导的肌醇磷酸生成，Ki分别为0.34μM和0.93μM。

Technical details

Catalog Num	A11966
M. Wt	488.98
Formula	C24H25ClN2O5S
Purity	>98%
Storage	at -20°C 3 years Powder
CAS No.	355025-13-7
Synonyms	Ki-16198
SMILES	CC1=NOC(=C1NC(=O)OC(C)C2=CC=CC=C2Cl)C3=CC=C(C=C3)CSCCC(=O)OC

Biological Activity

Ki16198是有效的LPA受体拮抗剂，可抑制LPA1和LPA3诱导的肌醇磷酸生成，Ki分别为0.34μM和0.93μM。

Targets

LPA1	LPA3
0.34 μM(Ki)	0.93 μM(Ki)

Solubility *

In vitro (25°C)	DMSO	86 mg/mL (175.87 mM)
	Water	Insoluble
	Ethanol	32 mg/mL (65.44 mM)
In vivo	1% DMSO+30% polyethylene glycol+1% Tween 80	28 mg/mL
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	20.45 mL	102.25 mL	204.51 mL
0.5 mM	4.09 mL	20.45 mL	40.9 mL
1 mM	2.05 mL	10.23 mL	20.45 mL
5 mM	0.41 mL	2.05 mL	4.09 mL

*The above data is based on the productmolecular weight 488.98. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.