GW 9662

Catalog No. A11984

GW 9662是一种选择性PPARγ拮抗剂(PPARγ,PPARα和PPARδ的IC50值分别为3.3、32和2000 nM)。
Catalog Num A11984
M. Wt 276.68
Formula C13H9N2O3Cl
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 22978-25-2
Synonyms GW9662, GW-9662
SMILES C1=CC=C(C=C1)NC(=O)C2=C(C=CC(=C2)[N+](=O)[O-])Cl
GW 9662是一种选择性PPARγ拮抗剂(PPARγ,PPARα和PPARδ的IC50值分别为3.3、32和2000 nM)。
Targets
PPARγ (Cell-free assay) PPARα (Cell-free assay) PPARδ (Cell-free assay)
3.3 nM32 nM2 μM
In vitro (25°C) DMSO 48 mg/mL (173.48 mM)
Water Insoluble
Ethanol Insoluble
In vivo 5% DMSO+corn oil 8 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 36.14 mL 180.71 mL 361.43 mL
0.5 mM 7.23 mL 36.14 mL 72.29 mL
1 mM 3.61 mL 18.07 mL 36.14 mL
5 mM 0.72 mL 3.61 mL 7.23 mL

*The above data is based on the productmolecular weight 276.68. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.