GW 9662
Catalog No. A11984
GW 9662是一种选择性PPARγ拮抗剂(PPARγ,PPARα和PPARδ的IC50值分别为3.3、32和2000 nM)。
Catalog Num | A11984 |
---|---|
M. Wt | 276.68 |
Formula | C13H9N2O3Cl |
Purity | >98% |
Storage | at -20°C 3 years Powder |
CAS No. | 22978-25-2 |
Synonyms | GW9662, GW-9662 |
SMILES | C1=CC=C(C=C1)NC(=O)C2=C(C=CC(=C2)[N+](=O)[O-])Cl |
GW 9662是一种选择性PPARγ拮抗剂(PPARγ,PPARα和PPARδ的IC50值分别为3.3、32和2000 nM)。
Targets
PPARγ (Cell-free assay) | PPARα (Cell-free assay) | PPARδ (Cell-free assay) | ||
3.3 nM | 32 nM | 2 μM |
In vitro (25°C) | DMSO | 48 mg/mL (173.48 mM) | |
Water | Insoluble | ||
Ethanol | Insoluble | ||
In vivo | 5% DMSO+corn oil | 8 mg/mL | |
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
---|---|---|---|
0.1 mM | 36.14 mL | 180.71 mL | 361.43 mL |
0.5 mM | 7.23 mL | 36.14 mL | 72.29 mL |
1 mM | 3.61 mL | 18.07 mL | 36.14 mL |
5 mM | 0.72 mL | 3.61 mL | 7.23 mL |
*The above data is based on the productmolecular weight 276.68. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.