Apocynin (Acetovanillone)

Catalog No. A11989

Apocynin (Acetovanillone)是NADPH氧化酶抑制剂。

Product Citations

Liling Su, .et al. Disruption of mitochondrial redox homeostasis as a mechanism of antimony-induced reactive oxygen species and cytotoxicity, Ecotoxicol Environ Saf, 2022, Jun 1;237:113519 PMID: 35453021
Shimizu S, .et al. Angiotensin II, a stress-related neuropeptide in the CNS, facilitates micturition reflex in rats, Br J Pharmacol, 2018, Sep;175(18):3727-3737 PMID: 29981238

Technical details

Catalog Num	A11989
M. Wt	166.17
Formula	C9H10O3
Purity	>98%
Storage	at -20°C 3 years Powder
CAS No.	498-02-2
Synonyms
SMILES	CC(=O)C1=CC(=C(C=C1)O)OC

Biological Activity

Apocynin (Acetovanillone)是NADPH氧化酶抑制剂。

Targets

NADPH-oxidase
10 μM

Solubility *

In vitro (25°C)	DMSO	32 mg/mL (192.57 mM)
	Water	Insoluble
	Ethanol	32 mg/mL (192.57 mM)
In vivo	2% DMSO+30% PEG 300+ddH2O	4 mg/mL
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	60.18 mL	300.9 mL	601.79 mL
0.5 mM	12.04 mL	60.18 mL	120.36 mL
1 mM	6.02 mL	30.09 mL	60.18 mL
5 mM	1.2 mL	6.02 mL	12.04 mL

*The above data is based on the productmolecular weight 166.17. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.