Betulinic acid

Catalog No. A11999

Betulinic acid是天然存在的五环三萜，具有抗逆转录病毒，抗疟疾和抗炎特性。

Technical details

Catalog Num	A11999
M. Wt	456.7
Formula	C30H48O3
Purity	>98%
Storage	at -20°C 3 years Powder
CAS No.	472-15-1
Synonyms
SMILES	CC(=C)[C@@H]1CC[C@]2([C@H]1[C@H]3CC[C@@H]4[C@]5(CC[C@@H](C([C@@H]5CC[C@]4([C@@]3(CC2)C)C)(C)C)O)C)C(=O)O

Biological Activity

Betulinic acid是天然存在的五环三萜，具有抗逆转录病毒，抗疟疾和抗炎特性。

Targets

HIV-1	Eukaryotic topoisomerase I	Aminopeptidase N
1.4 μM(EC50)	5 μM	7.3 μM

Solubility *

In vitro	DMSO	17 mg/mL (37.22 mM)
	Water	Insoluble
	Ethanol	9 mg/mL (19.7 mM)
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	21.9 mL	109.48 mL	218.96 mL
0.5 mM	4.38 mL	21.9 mL	43.79 mL
1 mM	2.19 mL	10.95 mL	21.9 mL
5 mM	0.44 mL	2.19 mL	4.38 mL

*The above data is based on the productmolecular weight 456.7. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.