Anamorelin

Catalog No. A12346

Anamorelin是一种新型 ghrelin receptor激动剂，FLIPR 检测中，EC50 为 0.74 nM，用于治疗与恶病质/厌食症相关的非小肺癌。

Product Citations

Josua Jordi, .et al. High-throughput screening for selective appetite modulators: A multibehavioral and translational drug discovery strategy, Sci Adv, 2018, Oct; 4(10): eaav1966 PMID: 30402545

Technical details

Catalog Num	A12346
M. Wt	546.7
Formula	C31H42N6O3
Purity	>98%
Storage	at -20°C 3 years Powder
CAS No.	249921-19-5
Synonyms
SMILES	CC(C)(C(=O)N[C@H](CC1=CNC2=CC=CC=C21)C(=O)N3CCC[C@](C3)(CC4=CC=CC=C4)C(=O)N(C)N(C)C)N

Biological Activity

Anamorelin是一种新型 ghrelin receptor激动剂，FLIPR 检测中，EC50 为 0.74 nM，用于治疗与恶病质/厌食症相关的非小肺癌。

Solubility *

In vitro	DMSO	92 mg/mL (168.28 mM)
	Water	Insoluble
	Ethanol	73 mg/mL (133.53 mM)
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	18.29 mL	91.46 mL	182.92 mL
0.5 mM	3.66 mL	18.29 mL	36.58 mL
1 mM	1.83 mL	9.15 mL	18.29 mL
5 mM	0.37 mL	1.83 mL	3.66 mL

*The above data is based on the productmolecular weight 546.7. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.