GSK 269962
Catalog No. A12348
GSK 269962是一种强效Rho激酶(ROCK)抑制剂(重组人ROCK1和ROCK2的IC50值分别为1.6和4 nM)。
- Praneeth Siripurapu, .et al. Two independent but synchronized Gβγ subunit-controlled pathways are essential for trailing-edge retraction during macrophage migration, J Biol Chem, 2017, Oct 20; 292(42): 17482-17495 PMID: 28864771
| Catalog Num | A12348 |
|---|---|
| M. Wt | 570.6 |
| Formula | C29H30N8O5 |
| Purity | >98% |
| Storage | at -20°C 3 years Powder |
| CAS No. | 850664-21-0 |
| Synonyms | GSK269962,GSK-269962, GSK269962A, GSK-269962A |
| SMILES | CCN1C2=CC(=NC=C2N=C1C3=NON=C3N)OC4=CC=CC(=C4)NC(=O)C5=CC=C(C=C5)OCCN6CCOCC6 |
GSK 269962是一种强效Rho激酶(ROCK)抑制剂(重组人ROCK1和ROCK2的IC50值分别为1.6和4 nM)。
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 17.53 mL | 87.63 mL | 175.25 mL |
| 0.5 mM | 3.51 mL | 17.53 mL | 35.05 mL |
| 1 mM | 1.75 mL | 8.76 mL | 17.53 mL |
| 5 mM | 0.35 mL | 1.75 mL | 3.51 mL |
*The above data is based on the productmolecular weight 570.6. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
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