MKT 077

Catalog No. A12388

MKT 077的p53结合位点,并使p53易位至细胞核。选择性细胞毒性;导致培养物中癌细胞生长停滞。也抑制端粒酶活性和交联f-肌动蛋白。
Catalog Num A12388
M. Wt 432
Formula C21H22ClN3OS2
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 147366-41-4
Synonyms MKT077, MKT-077
SMILES CCN1/C(=C/C2=CC=CC=[N+]2CC)/S/C(=C/3\N(C4=CC=CC=C4S3)C)/C1=O.[Cl-]
MKT 077的p53结合位点,并使p53易位至细胞核。选择性细胞毒性;导致培养物中癌细胞生长停滞。也抑制端粒酶活性和交联f-肌动蛋白。
In vitro DMSO 11 mg/mL (25.46 mM)
Water 75 mg/mL (173.61 mM)
Ethanol 9 mg/mL (20.83 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 23.15 mL 115.74 mL 231.48 mL
0.5 mM 4.63 mL 23.15 mL 46.3 mL
1 mM 2.31 mL 11.57 mL 23.15 mL
5 mM 0.46 mL 2.31 mL 4.63 mL

*The above data is based on the productmolecular weight 432. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.