TCS 359

Catalog No. A12427

TCS 359是一种有效的FLT3受体酪氨酸激酶抑制剂（IC50 = 42 nM），对多种其他激酶具有选择性。

Technical details

Catalog Num	A12427
M. Wt	360.43
Formula	C18H20N2O4S
Purity	>98%
Storage	at -20°C 3 years Powder
CAS No.	301305-73-7
Synonyms	TCS359, TCS-359
SMILES	COC1=C(C=C(C=C1)C(=O)NC2=C(C3=C(S2)CCCC3)C(=O)N)OC

Biological Activity

TCS 359是一种有效的FLT3受体酪氨酸激酶抑制剂（IC50 = 42 nM），对多种其他激酶具有选择性。

Targets

FLT3
42 nM

Solubility *

In vitro	DMSO	14 mg/mL (38.84 mM)
	Water	Insoluble
	Ethanol	Insoluble
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	27.74 mL	138.72 mL	277.45 mL
0.5 mM	5.55 mL	27.74 mL	55.49 mL
1 mM	2.77 mL	13.87 mL	27.74 mL
5 mM	0.55 mL	2.77 mL	5.55 mL

*The above data is based on the productmolecular weight 360.43. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.