MLN 0905

Catalog No. A12429

MLN0905是有效的选择性小分子PLK1抑制剂。MLN0905抑制包括DLBCL细胞系在内的多种人类肿瘤细胞的细胞增殖。

Technical details

Catalog Num	A12429
M. Wt	486.56
Formula	C24H25F3N6S
Purity	>98%
Storage	at -20°C 3 years Powder
CAS No.	1228960-69-7
Synonyms	MLN-0905,MLN0905
SMILES	CC1=C(C=C(C=N1)CCCN(C)C)NC2=NC=C3CC(=S)NC4=C(C3=N2)C=CC(=C4)C(F)(F)F

Biological Activity

MLN0905是有效的选择性小分子PLK1抑制剂。MLN0905抑制包括DLBCL细胞系在内的多种人类肿瘤细胞的细胞增殖。

Targets

PLK1
2 nM

Solubility *

In vitro	DMSO	93 mg/mL (191.13 mM)
	Water	Insoluble
	Ethanol	Insoluble
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	20.55 mL	102.76 mL	205.52 mL
0.5 mM	4.11 mL	20.55 mL	41.1 mL
1 mM	2.06 mL	10.28 mL	20.55 mL
5 mM	0.41 mL	2.06 mL	4.11 mL

*The above data is based on the productmolecular weight 486.56. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.