Pifithrin-u
Catalog No. A12449
Pifithrin-u通过降低p53与抗凋亡蛋白Bcl-2和Bcl-XL的亲和力来抑制p53与线粒体的结合。
Catalog Num | A12449 |
---|---|
M. Wt | 181.21 |
Formula | C8H7NO2S |
Purity | >98% |
Storage | at -20°C 3 years Powder |
CAS No. | 64984-31-2 |
Synonyms | NSC 303580 |
SMILES | C1=CC=C(C=C1)C#CS(=O)(=O)N |
Pifithrin-u通过降低p53与抗凋亡蛋白Bcl-2和Bcl-XL的亲和力来抑制p53与线粒体的结合。
Targets
p53 | ||||
In vitro (25°C) | DMSO | 33 mg/mL (182.11 mM) | |
Water | Insoluble | ||
Ethanol | 33 mg/mL (182.11 mM) | ||
In vivo | 2% DMSO+30% PEG 300+ddH2O | 4 mg/mL | |
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
---|---|---|---|
0.1 mM | 55.18 mL | 275.92 mL | 551.85 mL |
0.5 mM | 11.04 mL | 55.18 mL | 110.37 mL |
1 mM | 5.52 mL | 27.59 mL | 55.18 mL |
5 mM | 1.1 mL | 5.52 mL | 11.04 mL |
*The above data is based on the productmolecular weight 181.21. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.