MK-571

Catalog No. A12529

MK-571是有效的CysLT1（LTD4）白三烯受体反向激动剂，EC50值为1.3 nM。

Product Citations

Jung-Hung Chen, .et al. Transplacental transfer of acetaminophen in pregnant rats, Biomed Pharmacother, 2022, Oct;154:113613 PMID: 36058146

Technical details

Catalog Num	A12529
M. Wt	515.09
Formula	C26H27ClN2O3S2
Purity	>98%
Storage	at -20°C 3 years Powder
CAS No.	115104-28-4
Synonyms	L-660711, MK571, MK 571
SMILES	ClC1=CC=C2C(N=C(/C=C/C3=CC=CC(C(SCCC(O)=O)SCCC(N(C)C)=O)=C3)C=C2)=C1

Biological Activity

MK-571是有效的CysLT1（LTD4）白三烯受体反向激动剂，EC50值为1.3 nM。

Solubility *

In vitro	DMSO	93 mg/mL (180.55 mM)
	Water	Insoluble
	Ethanol	18 mg/mL (34.94 mM)
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	19.41 mL	97.07 mL	194.14 mL
0.5 mM	3.88 mL	19.41 mL	38.83 mL
1 mM	1.94 mL	9.71 mL	19.41 mL
5 mM	0.39 mL	1.94 mL	3.88 mL

*The above data is based on the productmolecular weight 515.09. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.