MS023

Catalog No. A12585

MS023是PRMT 1、3、4、6和8(IC50分别为30、119、83、8和8 nM)的有效抑制剂,它们负责精氨酸残基的不对称二甲基化。
Catalog Num A12585
M. Wt 287.4
Formula C17H25N3O
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 1831110-54-3
Synonyms MS-023, MS 023
SMILES NCCN(C)CC1=CNC=C1C2=CC=C(OC(C)C)C=C2
MS023是PRMT 1、3、4、6和8(IC50分别为30、119、83、8和8 nM)的有效抑制剂,它们负责精氨酸残基的不对称二甲基化。
Targets
PRMT6 PRMT8 PRMT1 PRMT4 PRMT3
4 nM5 nM30 nM83 nM119 nM
In vitro DMSO 50 mg/mL (173.96 mM)
Water Insoluble
Ethanol 50 mg/mL (173.96 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 34.79 mL 173.97 mL 347.95 mL
0.5 mM 6.96 mL 34.79 mL 69.59 mL
1 mM 3.48 mL 17.4 mL 34.79 mL
5 mM 0.7 mL 3.48 mL 6.96 mL

*The above data is based on the productmolecular weight 287.4. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.