Tasquinimod

Catalog No. A12616

Tasquinimod是一种变构抑制HDAC4信号传导的口服活性抗血管生成剂。

Technical details

Catalog Num	A12616
M. Wt	406.36
Formula	C20H17F3N2O4
Purity	>98%
Storage	at -20°C 3 years Powder
CAS No.	254964-60-8
Synonyms	ABR-215050
SMILES	CN1C2=C(C(=CC=C2)OC)C(=C(C1=O)C(=O)N(C)C3=CC=C(C=C3)C(F)(F)F)O

Biological Activity

Tasquinimod是一种变构抑制HDAC4信号传导的口服活性抗血管生成剂。

Targets

HDAC4

Solubility *

In vitro (25°C)	DMSO	78 mg/mL (191.95 mM)
	Water	Insoluble
	Ethanol	Warmed: 11 mg/mL (27.06 mM)
In vivo	5% DMSO+30% PEG 300+ddH2O	7 mg/mL
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	24.61 mL	123.04 mL	246.09 mL
0.5 mM	4.92 mL	24.61 mL	49.22 mL
1 mM	2.46 mL	12.3 mL	24.61 mL
5 mM	0.49 mL	2.46 mL	4.92 mL

*The above data is based on the productmolecular weight 406.36. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.