VU 0364439

Catalog No. A12664

VU 0364439是mGlu4受体的正变构调节剂（PAM）（对于人mGlu4，体外EC50 = 19.8 nM）。

Technical details

Catalog Num	A12664
M. Wt	422.29
Formula	C18H13Cl2N3O3S
Purity	>98%
Storage	at -20°C 3 years Powder
CAS No.	1246086-78-1
Synonyms	VU0364439,VU-0364439
SMILES	C1=CC=C(C(=C1)NS(=O)(=O)C2=C(C=C(C=C2)NC(=O)C3=CC=CC=N3)Cl)Cl

Biological Activity

VU 0364439是mGlu4受体的正变构调节剂（PAM）（对于人mGlu4，体外EC50 = 19.8 nM）。

Targets

mGluR4
19.8 nM(EC50)

Solubility *

In vitro	DMSO	77 mg/mL (182.34 mM)
	Water	Insoluble
	Ethanol	Insoluble
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	23.68 mL	118.4 mL	236.8 mL
0.5 mM	4.74 mL	23.68 mL	47.36 mL
1 mM	2.37 mL	11.84 mL	23.68 mL
5 mM	0.47 mL	2.37 mL	4.74 mL

*The above data is based on the productmolecular weight 422.29. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.