GSK1278863 (Daprodustat)

Catalog No. A12671

GSK1278863是新型的HIF-脯氨酰羟化酶抑制剂。

Technical details

Catalog Num	A12671
M. Wt	393.44
Formula	C19H27N3O6
Purity	>98%
Storage	at -20°C 3 years Powder
CAS No.	960539-70-2
Synonyms	Daprodustat, GSK 1278863, GSK-1278863
SMILES	O=C(O)CNC(C(C(N1C2CCCCC2)=O)C(N(C3CCCCC3)C1=O)=O)=O

Biological Activity

GSK1278863是新型的HIF-脯氨酰羟化酶抑制剂。

Targets

HIF-PH

Solubility *

In vitro	DMSO	Warmed: 9 mg/mL (22.87 mM)
	Water	Insoluble
	Ethanol	Insoluble
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	25.42 mL	127.08 mL	254.17 mL
0.5 mM	5.08 mL	25.42 mL	50.83 mL
1 mM	2.54 mL	12.71 mL	25.42 mL
5 mM	0.51 mL	2.54 mL	5.08 mL

*The above data is based on the productmolecular weight 393.44. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.