NVP-BAW2881

Catalog No. A12693

NVP-BAW2881是有效的选择性VEGFR抑制剂(血管内皮生长因子受体酪氨酸激酶抑制剂),IC50 为值9 nM,具有抑制慢性和急性皮肤炎症的作用。
Catalog Num A12693
M. Wt 424.1147
Formula C22H15F3N4O2
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 861875-60-7
Synonyms BAW2881, BAW-2881, BAW 2881, NVP-BAW-2881, NVP-BAW 2881
SMILES O=C(NC1=CC(C(F)(F)F)=CC=C1)C2=CC=CC3=C2C=CC(OC4=CC=NC(N)=N4)=C3
NVP-BAW2881是有效的选择性VEGFR抑制剂(血管内皮生长因子受体酪氨酸激酶抑制剂),IC50 为值9 nM,具有抑制慢性和急性皮肤炎症的作用。
Targets
Target Value
TIE-2
hVEGFR2IC50: 9nM
C-Raf-1IC50: 24nM
B-RAFV599EIC50: 76nM
c-AblIC50: 99nM
mVEGF2IC50: 165nM
RETIC50: 410nM
hVEGFR3IC50: 420nM
hVEGFR1IC50: 820nM
c-KITIC50: 2.5μM
In vitro DMSO 76 mg/mL (179.08 mM)
Water Insoluble
Ethanol 18 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 23.58 mL 117.89 mL 235.79 mL
0.5 mM 4.72 mL 23.58 mL 47.16 mL
1 mM 2.36 mL 11.79 mL 23.58 mL
5 mM 0.47 mL 2.36 mL 4.72 mL

*The above data is based on the productmolecular weight 424.1147. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.