Epoxomicin

Catalog No. A12730

Epoxomicin是从放线菌中分离出来的一种有效的抗肿瘤药，被用作20S蛋白酶体的选择性和不可逆抑制剂。

Technical details

Catalog Num	A12730
M. Wt	554.7
Formula	C28H50N4O7
Purity	>98%
Storage	at -20°C 3 years Powder
CAS No.	134381-21-8
Synonyms	BU-4061T
SMILES	CC[C@H](C)[C@@H](NC(=O)[C@H]([C@@H](C)CC)N(C)C(=O)C)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@H](CC(C)C)C(=O)[C@]1(C)OC1

Biological Activity

Epoxomicin是从放线菌中分离出来的一种有效的抗肿瘤药，被用作20S蛋白酶体的选择性和不可逆抑制剂。

Targets

20S proteasome

Solubility *

In vitro	DMSO	98 mg/mL (176.66 mM)
	Water	Insoluble
	Ethanol	98 mg/mL (176.66 mM)
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	18.03 mL	90.14 mL	180.28 mL
0.5 mM	3.61 mL	18.03 mL	36.06 mL
1 mM	1.8 mL	9.01 mL	18.03 mL
5 mM	0.36 mL	1.8 mL	3.61 mL

*The above data is based on the productmolecular weight 554.7. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.