GSK 2334470

Catalog No. A12767

GSK 2334470是一种有效的3-磷酸肌醇依赖性蛋白激酶（PDK1）抑制剂（IC50?10 nM）。

Technical details

Catalog Num	A12767
M. Wt	462.59
Formula	C25H34N8O
Purity	>98%
Storage	at -20°C 3 years Powder
CAS No.	1227911-45-6
Synonyms	GSK-2334470, GSK2334470
SMILES	C[C@@H]1CC[C@@H](CN1C2=NC(=NC(=C2)C3=CC4=C(C=C3)C(=NN4)N)NC)C(=O)NC5CCCCC5

Biological Activity

GSK 2334470是一种有效的3-磷酸肌醇依赖性蛋白激酶（PDK1）抑制剂（IC50?10 nM）。

Targets

PDK-1 (Cell-free assay)
10 nM

Solubility *

In vitro	DMSO	82 mg/mL (177.26 mM)
	Water	Insoluble
	Ethanol	82 mg/mL (177.26 mM)
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	21.62 mL	108.09 mL	216.17 mL
0.5 mM	4.32 mL	21.62 mL	43.23 mL
1 mM	2.16 mL	10.81 mL	21.62 mL
5 mM	0.43 mL	2.16 mL	4.32 mL

*The above data is based on the productmolecular weight 462.59. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.