Talmapimod (SCIO-469)
Catalog No. A12770
Talmapimod (SCIO-469)是一种具有ATP竞争性的选择性p38抑制剂（体外p38α的IC50 = 9 nM）。
| Catalog Num | A12770 |
|---|---|
| M. Wt | 549.46 |
| Formula | C27H31Cl2FN4O3 |
| Purity | >98% |
| Storage | at -20°C 3 years Powder |
| CAS No. | 309913-83-5 |
| Synonyms | SCIO469, SCIO 469 |
| SMILES | C[C@@H]1CN([C@H](CN1C(=O)C2=C(C=C3C(=C2)C(=CN3C)C(=O)C(=O)N(C)C)Cl)C)CC4=CC=C(C=C4)F |
Talmapimod (SCIO-469)是一种具有ATP竞争性的选择性p38抑制剂（体外p38α的IC50 = 9 nM）。
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 18.2 mL | 91 mL | 182 mL |
| 0.5 mM | 3.64 mL | 18.2 mL | 36.4 mL |
| 1 mM | 1.82 mL | 9.1 mL | 18.2 mL |
| 5 mM | 0.36 mL | 1.82 mL | 3.64 mL |
*The above data is based on the productmolecular weight 549.46. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
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