PS-1145

Catalog No. A12789

PS-1145是一种高度特异性的IKB激酶（IKK）抑制剂，可有效抑制PC细胞的基础和诱导型NF-kB活性。

Technical details

Catalog Num	A12789
M. Wt	322.75
Formula	C17H11ClN4O
Purity	>98%
Storage	at -20°C 3 years Powder
CAS No.	431898-65-6
Synonyms	PS1145,PS 1145
SMILES	C1=CC(=CN=C1)C(=O)NC2=C3C(=CC(=C2)Cl)C4=C(N3)C=NC=C4

Biological Activity

PS-1145是一种高度特异性的IKB激酶（IKK）抑制剂，可有效抑制PC细胞的基础和诱导型NF-kB活性。

Targets

IKK
88 nM

Solubility *

In vitro	DMSO	61 mg/mL (189 mM)
	Water	Insoluble
	Ethanol	Warmed: 2 mg/mL (6.19 mM)
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	30.98 mL	154.92 mL	309.84 mL
0.5 mM	6.2 mL	30.98 mL	61.97 mL
1 mM	3.1 mL	15.49 mL	30.98 mL
5 mM	0.62 mL	3.1 mL	6.2 mL

*The above data is based on the productmolecular weight 322.75. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.