Ro 61-8048

Catalog No. A12833

Ro 61-8048是有效的竞争性犬尿氨酸3-羟化酶抑制剂（Ki = 4.8 nM，IC50 = 37 nM）。

Technical details

Catalog Num	A12833
M. Wt	421.45
Formula	C17H15N3O6S2
Purity	>98%
Storage	at -20°C 3 years Powder
CAS No.	199666-03-0
Synonyms	Ro61-8048
SMILES	COC1=C(C=C(C=C1)S(=O)(=O)NC2=NC(=CS2)C3=CC(=CC=C3)[N+](=O)[O-])OC

Biological Activity

Ro 61-8048是有效的竞争性犬尿氨酸3-羟化酶抑制剂（Ki = 4.8 nM，IC50 = 37 nM）。

Targets

KMO	KMO
4.8 nM(Ki)	37 nM

Solubility *

In vitro (25°C)	DMSO	80 mg/mL (189.82 mM)
	Water	Insoluble
	Ethanol	Insoluble
In vivo	2% DMSO+30% PEG 300+5% Tween 80+ddH2O	9 mg/mL
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	23.73 mL	118.64 mL	237.28 mL
0.5 mM	4.75 mL	23.73 mL	47.46 mL
1 mM	2.37 mL	11.86 mL	23.73 mL
5 mM	0.47 mL	2.37 mL	4.75 mL

*The above data is based on the productmolecular weight 421.45. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.