NQDI 1

Catalog No. A12838

NQDI 1是细胞凋亡信号调节激酶1（ASK1，MAP3K5）的选择性抑制剂（IC50 = 3 μM，Ki = 500 nM）。

Technical details

Catalog Num	A12838
M. Wt	319.31
Formula	C19H13NO4
Purity	>98%
Storage	at -20°C 3 years Powder
CAS No.	175026-96-7
Synonyms	NQDI-1, NQDI1
SMILES	O=C1NC2=CC=CC3=C2C(C4=CC=CC=C4C3=O)=C1C(OCC)=O

Biological Activity

NQDI 1是细胞凋亡信号调节激酶1（ASK1，MAP3K5）的选择性抑制剂（IC50 = 3 μM，Ki = 500 nM）。

Targets

ASK1

Solubility *

In vitro (25°C)	DMSO	20 mg/mL (62.63 mM)
	Water	Insoluble
	Ethanol	Insoluble
In vivo	5%dmso+40%PEG300+5%tween-80+ddH2O	0.4 mg/mL
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	31.32 mL	156.59 mL	313.18 mL
0.5 mM	6.26 mL	31.32 mL	62.64 mL
1 mM	3.13 mL	15.66 mL	31.32 mL
5 mM	0.63 mL	3.13 mL	6.26 mL

*The above data is based on the productmolecular weight 319.31. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.