Refametinib (RDEA-119, BAY 86-9766)
Catalog No. A12866
Refametinib (RDEA-119,BAY 86-9766)是一种口服生物利用型选择性MEK抑制剂，EC50为 2.0-15 nM。具有潜在的抗肿瘤活性。
| Catalog Num | A12866 |
|---|---|
| M. Wt | 572.34 |
| Formula | C19H20F3IN2O5S |
| Purity | >98% |
| Storage | at -20°C 3 years Powder |
| CAS No. | 923032-38-6 |
| Synonyms | RDEA119, RDEA 119, BAY 86-9766, BAY 869766, BAY869766 |
| SMILES | COC1=CC(=C(C(=C1NS(=O)(=O)C2(CC2)C[C@H](CO)O)NC3=C(C=C(C=C3)I)F)F)F |
Refametinib (RDEA-119,BAY 86-9766)是一种口服生物利用型选择性MEK抑制剂，EC50为 2.0-15 nM。具有潜在的抗肿瘤活性。
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 17.47 mL | 87.36 mL | 174.72 mL |
| 0.5 mM | 3.49 mL | 17.47 mL | 34.94 mL |
| 1 mM | 1.75 mL | 8.74 mL | 17.47 mL |
| 5 mM | 0.35 mL | 1.75 mL | 3.49 mL |
*The above data is based on the productmolecular weight 572.34. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
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