BAM 7

Catalog No. A12907

BAM 7使用FITC-BIM SAHB和BAX在竞争性FP分析中测得的EC50?3.3 μM结合BAX触发位点。

Product Citations

Takino JI, .et al. The inhibition of Bax activation-induced apoptosis by RasGRP2 via R-Ras-PI3K-Akt signaling pathway in the endothelial cells, Sci Rep, 2019, Nov 13;9(1):16717 PMID: 31723205

Technical details

Catalog Num	A12907
M. Wt	405.47
Formula	C21H19N5O2S
Purity	>98%
Storage	at -20°C 3 years Powder
CAS No.	331244-89-4
Synonyms	BAM7
SMILES	CCOC1=CC=CC=C1N/N=C/2\C(=NN(C2=O)C3=NC(=CS3)C4=CC=CC=C4)C

Biological Activity

BAM 7使用FITC-BIM SAHB和BAX在竞争性FP分析中测得的EC50?3.3 μM结合BAX触发位点。

Targets

Bax
3.3 μM(EC50)

Solubility *

In vitro	DMSO	2 mg/mL (4.93 mM)
	Water	Insoluble
	Ethanol	Insoluble
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	24.66 mL	123.31 mL	246.63 mL
0.5 mM	4.93 mL	24.66 mL	49.33 mL
1 mM	2.47 mL	12.33 mL	24.66 mL
5 mM	0.49 mL	2.47 mL	4.93 mL

*The above data is based on the productmolecular weight 405.47. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.