AM251

Catalog No. A12914

AM251是有效的CB1受体拮抗剂(IC50 = 8 nM,Ki = 7.49 nM),其选择性是CB2受体的306倍。
Catalog Num A12914
M. Wt 555.24
Formula C22H21Cl2IN4O
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 183232-66-8
Synonyms AM 251, AM-251
SMILES CC1=C(N(N=C1C(=O)NN2CCCCC2)C3=C(C=C(C=C3)Cl)Cl)C4=CC=C(C=C4)I
AM251是有效的CB1受体拮抗剂(IC50 = 8 nM,Ki = 7.49 nM),其选择性是CB2受体的306倍。
Targets
CB1
In vitro (25°C) DMSO 39 mg/mL (70.24 mM)
Water Insoluble
Ethanol Insoluble
In vivo 1% DMSO+30% polyethylene glycol+1% Tween 80 7 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 18.01 mL 90.05 mL 180.1 mL
0.5 mM 3.6 mL 18.01 mL 36.02 mL
1 mM 1.8 mL 9.01 mL 18.01 mL
5 mM 0.36 mL 1.8 mL 3.6 mL

*The above data is based on the productmolecular weight 555.24. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.