GSK J1

Catalog No. A12918

GSK J1是H3K27组蛋白脱甲基酶JMJD3和UTX的有效和选择性抑制剂。
  • Guang Bai, .et al. Chapter 1 - Epigenetic Tools in Chronic Pain Studies, Epigenetics of Chronic Pain, 2019, Pages 1-48
Catalog Num A12918
M. Wt 389.45
Formula C22H23N5O2
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 1373422-53-7
Synonyms 0
SMILES C1CN(CCC2=CC=CC=C21)C3=CC(=NC(=N3)C4=CC=CC=N4)NCCC(=O)O
GSK J1是H3K27组蛋白脱甲基酶JMJD3和UTX的有效和选择性抑制剂。
Targets
JMJD3 (KDM6B) UTX (KDM6A)
28 nM53 nM
In vitro DMSO 70 mg/mL (179.74 mM)
Water Insoluble
Ethanol Insoluble
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 25.68 mL 128.39 mL 256.77 mL
0.5 mM 5.14 mL 25.68 mL 51.35 mL
1 mM 2.57 mL 12.84 mL 25.68 mL
5 mM 0.51 mL 2.57 mL 5.14 mL

*The above data is based on the productmolecular weight 389.45. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.