Radotinib (IY-5511)

Catalog No. A13029

Radotinib是一种新型的选择性Bcl-Abl酪氨酸激酶抑制剂。

Technical details

Catalog Num	A13029
M. Wt	530.5
Formula	C27H21F3N8O
Purity	>98%
Storage	at -20°C 3 years Powder
CAS No.	926037-48-1
Synonyms	IY-5511
SMILES	CC1=C(C=C(C=C1)C(=O)NC2=CC(=CC(=C2)N3C=C(N=C3)C)C(F)(F)F)NC4=NC=CC(=N4)C5=NC=CN=C5

Biological Activity

Radotinib是一种新型的选择性Bcl-Abl酪氨酸激酶抑制剂。

Targets

BCR-ABL1
34 nM

Solubility *

In vitro	DMSO	94 mg/mL (177.19 mM)
	Water	Insoluble
	Ethanol	Insoluble
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	18.85 mL	94.25 mL	188.5 mL
0.5 mM	3.77 mL	18.85 mL	37.7 mL
1 mM	1.89 mL	9.43 mL	18.85 mL
5 mM	0.38 mL	1.89 mL	3.77 mL

*The above data is based on the productmolecular weight 530.5. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.